Cambrian FFPE gDNA Isolation Kit

Cambrian FFPE gDNA Isolation Kit

Cambrian FFPE gDNA Isolation Kit

Cambrian FFPE gDNA Isolation Kit

Built for FFPE variability. Designed for consistent results

Built for FFPE variability. Designed for consistent results

Built for FFPE variability. Designed for consistent results

Available pack size:

Available pack size:

50 reactions

50 reactions

250 reactions

250 reactions

Get reliable DNA from
FFPE samples

Get reliable DNA from FFPE samples

Get reliable DNA from
FFPE samples

Get reliable DNA from
FFPE samples

FFPE samples are the most widely used clinical specimens in oncology, but extracting sequencing-grade DNA from them is often unreliable due to variability in fixation and processing.

Our kit uses bead-based chemistry to consistently recover high quality DNA even at low tumor content (~10%), with broad fragment coverage (200 bp–48.5 kbp) and strong DIN values, making it ready for NGS and PCR workflows.

Consistency across
FFPE variability

Built for Indian FFPE samples

Built for Indian FFPE samples

Built for Indian FFPE samples

Optimized to handle variability in paraffin and formalin quality across regions

Consistent DNA quality

Consistent DNA quality

Consistent DNA quality

The kit delivers reliable DNA extraction across variable FFPE blocks

Flexible lysis options

Flexible lysis options

Flexible lysis options

Choose between 2-hour or overnight lysis (16 hr) based on workflow needs

Safer deparaffinization

Safer deparaffinization

The kit uses mineral oil for deparaffinization, eliminating the need for a fume hood and enabling a non-toxic, safer workflow

The kit uses mineral oil for deparaffinization, eliminating the need for a fume hood and enabling a non-toxic, safer workflow

Designed for oncology workflows

Designed for oncology workflows

Designed for oncology workflows

Supports CGP, Oncomine, TSO, and custom oncology panels

Supports CGP, Oncomine, TSO, and custom oncology panels

Enabling a wide range of oncology
workflows from FFPE samples

Enabling a wide range of oncology workflows from FFPE samples

The Cambrian FFPE gDNA Isolation Kit supports high-quality DNA extraction for a broad set of downstream applications, including:

The Cambrian FFPE gDNA Isolation Kit supports high-quality DNA extraction for a broad set of downstream applications, including:

Somatic mutation profiling

Analysis of key genes such as

TP53

KRAS

EGFR

BRAF

Germline variant analysis

Identification of variants from tumor DNA such as

BRCA1/2

MLH1

Comprehensive genomic profiling (CGP)

Multi-gene panels assessing mutations, fusions, CNVs, MSI, and TMB

Tumor mutational burden (TMB) assessment

Used in immunotherapy response evaluation like

PD-1

PD-L1

Microsatellite instability (MSI) testing

Relevant for colorectal cancer and immunotherapy eligibility

Fusion gene detection

This includes fusions like

ALK

ROS1

RET

NTRK

Copy number variation (CNV) analysis

Detection of amplifications like

HER2

MET

EGFR

and deletions like

CDKN2A

PTEN

Retrospective cohort and biomarker studies

Leveraging archival FFPE samples for translational research

Tumor heterogeneity studies

Understanding clonal variation and resistance mechanisms

Somatic mutation profiling

Analysis of key genes such as

TP53

KRAS

EGFR

BRAF

Copy number variation (CNV) analysis

Detection of amplifications like

HER2

MET

EGFR

and deletions like

CDKN2A

PTEN

Microsatellite instability (MSI) testing

Relevant for colorectal cancer and immunotherapy eligibility

Comprehensive genomic profiling (CGP)

Multi-gene panels assessing mutations, fusions, CNVs, MSI, and TMB

Tumor heterogeneity studies

Understanding clonal variation and resistance mechanisms

Tumor mutational burden (TMB) assessment

Used in immunotherapy response evaluation like

PD-1

PD-L1

Germline variant analysis

Identification of variants from tumor DNA such as

BRCA1/2

MLH1

Retrospective cohort and biomarker studies

Leveraging archival FFPE samples for translational research

Fusion gene detection

This includes fusions like

ALK

ROS1

RET

NTRK

Somatic mutation profiling

Analysis of key genes such as

TP53

KRAS

EGFR

BRAF

Tumor mutational burden (TMB) assessment

Used in immunotherapy response evaluation like

PD-1

PD-L1

Copy number variation (CNV) analysis

Detection of amplifications like

HER2

MET

EGFR

and deletions like

CDKN2A

PTEN

Germline variant analysis

Identification of variants from tumor DNA such as

BRCA1/2

MLH1

Microsatellite instability (MSI) testing

Relevant for colorectal cancer and immunotherapy eligibility

Retrospective cohort and biomarker studies

Leveraging archival FFPE samples for translational research

Comprehensive genomic profiling (CGP)

Multi-gene panels assessing mutations, fusions, CNVs, MSI, and TMB

Fusion gene detection

This includes fusions like

ALK

ROS1

RET

NTRK

Tumor heterogeneity studies

Understanding clonal variation and resistance mechanisms

Somatic mutation profiling

Analysis of key genes such as

TP53

KRAS

EGFR

BRAF

Tumor mutational burden (TMB) assessment

Used in immunotherapy response evaluation like

PD-1

PD-L1

Copy number variation (CNV) analysis

Detection of amplifications like

HER2

MET

EGFR

and deletions like

CDKN2A

PTEN

Germline variant analysis

Identification of variants from tumor DNA such as

BRCA1/2

MLH1

Microsatellite instability (MSI) testing

Relevant for colorectal cancer and immunotherapy eligibility

Retrospective cohort and biomarker studies

Leveraging archival FFPE samples for translational research

Comprehensive genomic profiling (CGP)

Multi-gene panels assessing mutations, fusions, CNVs, MSI, and TMB

Fusion gene detection

This includes fusions like

ALK

ROS1

RET

NTRK

Tumor heterogeneity studies

Understanding clonal variation and resistance mechanisms

Performance preview

See how the Cambrian FFPE DNA Extraction Kit performs on real-world tumour samples. This application note highlights DNA yield, integrity (DIN), and sequencing readiness across diverse FFPE tissues demonstrating reliable performance for NGS and PCR workflows.

Ordering information

Product

SKU

Pack Size

Workflow Type

Product

SKU

Pack Size

Workflow Type

Product

SKU

Pack Size

Workflow Type

Cambrian FFPE gDNA Isolation Kit

Cambrian FFPE gDNA Isolation Kit

CBWC100.50

CBWC100.50

50 reactions

50 reactions

Manual

Manual

Cambrian FFPE gDNA Isolation Kit

Cambrian FFPE gDNA Isolation Kit

CBWC100.250

CBWC100.250

250 reactions

250 reactions

Manual

Manual

Cambrian FFPE gDNA Isolation Kit for Manta

Cambrian FFPE gDNA Isolation Kit for Manta

CBWM100.64

CBWM100.64

64 reactions

64 reactions

Semi-automated (Manta)

Semi-automated (Manta)

Make FFPE extraction reliable

Handle variability with confidence and get consistent DNA from every block.