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Unlock the power of liquid biopsy with the OncoSeek cfDNA extraction kit

Unlock the power of liquid biopsy with the OncoSeek cfDNA extraction kit

Isolate high-yield RNA from FFPE blocks consistently

Isolate high-yield RNA from FFPE blocks consistently

Isolate high-quality cfDNA with high recovery and minimal genomic DNA contamination.

Isolate high-quality cfDNA with high recovery and minimal genomic DNA contamination.

Isolate high-quality cfDNA with high recovery and minimal genomic DNA contamination.

Isolate high-quality cfDNA with high recovery and minimal genomic DNA contamination.

Available pack size:

Available pack size:

Available pack size:

50 reactions

50 reactions

50 reactions

Built for sensitive
oncology workflows

Designed for the realities of oncology workflows

Optimized for oncology applications

Optimized for oncology applications

Optimized for oncology applications

Optimized for oncology applications

NGS

NGS

NGS

NGS

qPCR

qPCR

qPCR

qPCR

digital PCR

digital PCR

Optimized for liquid biopsy and MRD applications, supporting reliable detection of low-abundance ctDNA across

Optimized for liquid biopsy and MRD applications, supporting reliable detection of low-abundance ctDNA across

Optimized for liquid biopsy and MRD applications, supporting reliable detection of low-abundance ctDNA across

Efficient workflow

Efficient workflow

Efficient workflow

Efficient workflow

Bead-based purification reduces manual effort and supports automation, completing cfDNA extraction in ≈55 minutes.

Bead-based purification reduces manual effort and supports automation, completing cfDNA extraction in ≈55 minutes.

Bead-based purification reduces manual effort and supports automation, completing cfDNA extraction in ≈55 minutes.

Maximize yield from every sample

Maximize yield from every sample

Maximize yield from every sample

Maximize yield from every sample

Efficiently isolates cfDNA even from small plasma volumes, delivering consistent yields while preserving valuable sample material.

Efficiently isolates cfDNA even from small plasma volumes, delivering consistent yields while preserving valuable sample material.

Efficiently isolates cfDNA even from small plasma volumes, delivering consistent yields while preserving valuable sample material.

Enriched for tumor-relevant fragment sizes

Preferentially captures 150–200 bp cfDNA fragments, enriching tumor-derived DNA and improving detection sensitivity.

Preferentially captures 150–200 bp cfDNA fragments, enriching tumor-derived DNA and improving detection sensitivity.

Minimal genomic DNA contamination

Minimal genomic DNA contamination

Minimal genomic DNA contamination

Minimal genomic DNA contamination

Selective binding conditions help limit gDNA contamination.

Selective binding conditions help limit gDNA contamination.

Selective binding conditions help limit gDNA contamination.

Performance preview

Performance preview

Performance preview

Performance preview

Performance preview

RNA yield and purity datasets

RNA yield and purity datasets

RNA yield and purity datasets

RNA yield and purity datasets

RNA yield and purity datasets

From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.

From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.

From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.

From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.

Yield (ng)

Yield (ng)

A260/A280

A260/A280

A260/A230

A260/A230

Sample number

Qubit yield (ng)

500

1000

5000

10000

8

7

6

5

4

3

2

1

0.0

0.5

1.0

1.5

2.0

2.5

Purity ratio

Sample number

Qubit yield (ng)

500

1000

5000

10000

8

7

6

5

4

3

2

1

0.0

0.5

1.0

1.5

2.0

2.5

Purity ratio

Sample number

Qubit yield (ng)

500

1000

5000

10000

8

7

6

5

4

3

2

1

0.0

0.5

1.0

1.5

2.0

2.5

Purity ratio

RIN & DV200 values

RIN & DV200 values

RIN & DV200 values

RIN & DV200 values

RIN & DV200 values

DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.

DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.

DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.

DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.

Sample number

Sample number

Sample number

1

1

1

2

2

2

3

3

3

4

4

4

5

5

5

6

6

6

7

7

7

8

8

8

RIN

RIN

RIN

3.8

3.8

3.8

3.1

3.1

3.1

3.2

3.2

3.2

2.1

2.1

2.1

1.7

1.7

1.7

2.1

2.1

2.1

1.8

1.8

1.8

2.6

2.6

2.6

DV200 (%)

DV200 (%)

DV200 (%)

85.47

85.47

85.47

73.09

73.09

73.09

83.59

83.59

83.59

60.23

60.23

60.23

40.7

40.7

40.7

32.1

32.1

32.1

34.58

34.58

34.58

58.91

58.91

58.91

Optimized for
critical downstream assays

Gene expression profiling

Tumor subtype classification

Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)

Biomarker discovery & validation

Transcriptome studies

RNA fusions & splice variants

Retrospective clinical research

Manta empowers diverse molecular diagnostic applications including genetics lab, gut microbiome testing, germline mutation detection, microarray testing

Optimized for critical downstream assays

Gene expression profiling

Tumor subtype classification

Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)

Biomarker discovery & validation

Linking RNA signatures to prognosis

Therapy response

Disease progression

Transcriptome studies

Global expression profiling

Whole-transcriptome RNA-seq for personalized oncology

RNA fusions & splice variants

Detect clinically relevant gene fusions

Characterize splice isoforms linked to cancer biology

Retrospective clinical research

Mining archived FFPE archives for relapse, survival, and long-term outcome correlations

Optimized for
critical downstream assays

Gene expression profiling

Tumor subtype classification

Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)

Biomarker discovery & validation

Transcriptome studies

RNA fusions & splice variants

Retrospective clinical research

Manta empowers diverse molecular diagnostic applications including genetics lab, gut microbiome testing, germline mutation detection, microarray testing

Optimized for critical downstream assays

Gene expression profiling

Tumor subtype classification

Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)

Biomarker discovery & validation

Linking RNA signatures to prognosis

Therapy response

Disease progression

Transcriptome studies

Global expression profiling

Whole-transcriptome RNA-seq for personalized oncology

RNA fusions & splice variants

Detect clinically relevant gene fusions

Characterize splice isoforms linked to cancer biology

Retrospective clinical research

Mining archived FFPE archives for relapse, survival, and long-term outcome correlations

Optimized for
critical downstream assays

Gene expression profiling

Tumor subtype classification

Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)

Biomarker discovery & validation

Transcriptome studies

RNA fusions & splice variants

Retrospective clinical research

Manta empowers diverse molecular diagnostic applications including genetics lab, gut microbiome testing, germline mutation detection, microarray testing

Seamlessly integrates
with your lab needs

Seamlessly integrates
with your lab needs

Seamlessly integrates
with your lab needs

Seamlessly integrates
with your lab needs

Seamlessly integrates
with your lab needs

Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.

Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.

Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.

Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.

Build reliable liquid
biopsy workflows

Discover how OncoSeek can support your MRD, liquid biopsy, and oncology research applications.

Discover how OncoSeek can support your MRD, liquid biopsy, and oncology research applications.

Discover how OncoSeek can support your MRD, liquid biopsy, and oncology research applications.

Discover how OncoSeek can support your MRD, liquid biopsy, and oncology research applications.