Extracting DNA from blood samples is routine, but not always reliable. In clinical and diagnostic labs, inconsistent yields, poor purity, and sample prep complexity can slow down testing and compromise downstream analysis. Whether you're running NGS, HLA typing, or PCR workflows, the extraction step needs to be simple, scalable, and robust, even from difficult samples.

This app note showcases how the Manta platform simplifies and improves blood DNA extraction. It details the complete protocol using Cambrian’s cartridge-based system and buffers, built specifically for whole blood. The app note presents data from multiple labs, comparing Manta to two leading commercial kits. It includes side-by-side performance results on yield, purity, and DNA integrity across 128 samples, and real-world outcomes from low-WBC clinical samples where most kits fail.

The goal is to help labs improve extraction quality without adding complexity. You'll find practical insights on automation setup, sample prep, and QC, along with TapeStation profiles and workflow benchmarks.

Download now to explore the full protocol, compare results across kits, and see how Manta performs in high-throughput clinical settings.