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Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Quality that you can trust

Get the best start for your molecular workflows

Get the best start for your molecular workflows

Get the best start for your molecular workflows

“Above all else,

show data” - Edward Tufte

“Above all else,

show data” - Edward Tufte

“Above all else,

show data” - Edward Tufte

“Above all else,

show data” - Edward Tufte

Data is the strongest testament to quality—and that’s what makes it so powerful. We seek to earn the trust of our users and the broader healthcare community by showing the numbers upfront.

Data is the strongest testament to quality—and that’s what makes it so powerful. We seek to earn the trust of our users and the broader healthcare community by showing the numbers upfront.

Data is the strongest testament to quality—and that’s what makes it so powerful. We seek to earn the trust of our users and the broader healthcare community by showing the numbers upfront.

Data is the strongest testament to quality—and that’s what makes it so powerful. We seek to earn the trust of our users and the broader healthcare community by showing the numbers upfront.

Manta is engineered to handle diverse diagnostic samples, delivering high-quality DNA and RNA for downstream applications. Below we share data that was collected as part of our validation process to provide a performance preview of the device.

Manta is engineered to handle diverse diagnostic samples, delivering high-quality DNA and RNA for downstream applications. Below we share data that was collected as part of our validation process to provide a performance preview of the device.

Manta is engineered to handle diverse diagnostic samples, delivering high-quality DNA and RNA for downstream applications. Below we share data that was collected as part of our validation process to provide a performance preview of the device.

Manta is engineered to handle diverse diagnostic samples, delivering high-quality DNA and RNA for downstream applications. Below we share data that was collected as part of our validation process to provide a performance preview of the device.

Concentrated

on precision

Concentrated

on precision

Concentrated

on precision

Concentrated

on precision

Manta delivers high molecular weight and intact nucleic acids with efficiency and accuracy. Every step of our development was designed to meet the highest standards, ensuring consistent performance across diverse samples. The graph below highlights the concentration (ng/µL) achieved with various diagnostic sample types: whole blood, fresh tissue, saliva, body fluids, and FFPE.

Manta delivers high molecular weight and intact nucleic acids with efficiency and accuracy. Every step of our development was designed to meet the highest standards, ensuring consistent performance across diverse samples. The graph below highlights the concentration (ng/µL) achieved with various diagnostic sample types: whole blood, fresh tissue, saliva, body fluids, and FFPE.

Manta delivers high molecular weight and intact nucleic acids with efficiency and accuracy. Every step of our development was designed to meet the highest standards, ensuring consistent performance across diverse samples. The graph below highlights the concentration (ng/µL) achieved with various diagnostic sample types: whole blood, fresh tissue, saliva, body fluids, and FFPE.

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

1.00

10.00

100.00

1000.00

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

Cambrian

Company A

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

1.00

10.00

100.00

1000.00

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

Cambrian

Company A

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

1.00

10.00

100.00

1000.00

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

Cambrian

Company A

Cambrian

Company A

1.00

10.00

100.00

1000.00

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

Cambrian

Company A

1.00

10.00

100.00

1000.00

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

Cambrian

Company A

1.00

10.00

100.00

1000.00

Whole blood

Fresh tissue

Saliva

Body fluids

FFPE

DNA Concentration (ng/µL)

Note: This graph is in logarithmic scale

220

240

260

280

300

Wavelength (nm)

Absorbance

0

1

2

3

4

Stay ahead

of the curve

Stay ahead

of the curve

Stay ahead

of the curve

Stay ahead

of the curve

Manta is designed to deliver stable purity ratios—A260/A280 and A260/A230—with each run. Powered by magnetic beads, it consistently delivers the quality needed for smooth downstream applications.

Manta is designed to deliver stable purity ratios—A260/A280 and A260/A230—with each run. Powered by magnetic beads, it consistently delivers the quality needed for smooth downstream applications.

Manta is designed to deliver stable purity ratios—A260/A280 and A260/A230—with each run. Powered by magnetic beads, it consistently delivers the quality needed for smooth downstream applications.

220

2

0

1

3

4

Absorbance

Wavelength (nm)

240

260

280

300

220

2

0

1

3

4

Absorbance

Wavelength (nm)

240

260

280

300

220

Wavelength (nm)

240

260

280

300

2

0

1

3

4

Absorbance

220

Wavelength (nm)

240

260

280

300

2

0

1

3

4

Absorbance

220

Wavelength (nm)

240

260

280

300

2

0

1

3

4

Absorbance

Mastering the

toughest samples

Mastering the

toughest samples

Mastering the

toughest samples

Mastering the

toughest samples

The toughest samples demand the best results. Manta specializes in extracting nucleic acids from challenging FFPE samples, ensuring high DNA yields and DNA integrity numbers (DIN) for sequencing. This study included a diverse range of FFPE samples, from various tumor types and specimen sites, demonstrating the system's adaptability and reliability.

The toughest samples demand the best results. Manta specializes in extracting nucleic acids from challenging FFPE samples, ensuring high DNA yields and DNA integrity numbers (DIN) for sequencing. This study included a diverse range of FFPE samples, from various tumor types and specimen sites, demonstrating the system's adaptability and reliability.

The toughest samples demand the best results. Manta specializes in extracting nucleic acids from challenging FFPE samples, ensuring high DNA yields and DNA integrity numbers (DIN) for sequencing. This study included a diverse range of FFPE samples, from various tumor types and specimen sites, demonstrating the system's adaptability and reliability.

Endometrium

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovay

Prostate

Brain

Colon

Brain

1.00

10.00

100.00

1000.00

Note: This graph is in logarithmic scale

Total DNA yield (ng)

DIN

10%

15%

20%

30%

40%

50%

60%

70%

0

2

4

6

Tumour content

Peritoneum

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovary

Prostate

10%

20%

15%

Tumour content

Note: This graph is in logarithmic scale

Total DNA yield (ng)

1.00

10.00

100.00

1000.00

30%

40%

50%

60%

0

2

4

6

DIN

Peritoneum

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovary

Prostate

10%

20%

15%

Tumour content

Note: This graph is in logarithmic scale

Total DNA yield (ng)

1.00

10.00

100.00

1000.00

30%

40%

50%

60%

0

2

4

6

DIN

Peritoneum

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovary

Prostate

10%

20%

15%

Tumour content

Note: This graph is in logarithmic scale

Total DNA yield (ng)

1.00

10.00

100.00

1000.00

30%

40%

50%

60%

0

2

4

6

DIN

Peritoneum

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovary

Prostate

10%

20%

15%

Tumour content

Note: This graph is in logarithmic scale

Total DNA yield (ng)

1.00

10.00

100.00

1000.00

30%

40%

50%

60%

0

2

4

6

DIN

Peritoneum

Soft tissue

Breast

Brain

Omentum

Peritoneum

Soft tissue

Endometrium

Colon

Pelvic mass

Rectum

Soft tissue

Colon

Pleura

Rectum

Soft tissue

Lymph node

Omentum

Stomach

Rectum

Thyroid

Ovary

Prostate

10%

20%

15%

Tumour content

Note: This graph is in logarithmic scale

Total DNA yield (ng)

1.00

10.00

100.00

1000.00

30%

40%

50%

60%

0

2

4

6

DIN

0

1

2

3

4

100

250

400

600

900

1200

1500

2000

2500

Size(bp)

Sample intensity (Normalised FU)

Capturing

every detail

Capturing

every detail

Capturing

every detail

To ensure accurate results, we analyzed purified FFPE DNA using the TapeStation Analyzer. Across various samples, we observed full coverage of fragments of all sizes, making sure that even the smallest fragments were captured.

To ensure accurate results, we analyzed purified FFPE DNA using the TapeStation Analyzer. Across various samples, we observed full coverage of fragments of all sizes, making sure that even the smallest fragments were captured.

To ensure accurate results, we analyzed purified FFPE DNA using the TapeStation Analyzer. Across various samples, we observed full coverage of fragments of all sizes, making sure that even the smallest fragments were captured.

100

250

400

600

900

1200

1500

2000

2500

0

1

2

3

4

Sample intensity (Normalised FU)

Size(bp)

100

250

400

600

900

1200

1500

2000

2500

0

1

2

3

4

Sample intensity (Normalised FU)

Size(bp)

100

250

400

600

900

1200

1500

2000

2500

0

2

1

3

4

Sample intensity (Normalised FU)

Size(bp)

100

250

400

600

900

1200

1500

2000

2500

0

2

1

3

4

Sample intensity (Normalised FU)

Size(bp)

100

250

400

600

900

1200

1500

2000

2500

0

2

1

3

4

Sample intensity (Normalised FU)

Size(bp)

Testing

for accuracy

Testing

for accuracy

Testing

for accuracy

We recognize the critical role of DNA quality from FFPE blocks in NGS workflows. This data, generated using the Infinium HD FFPE QC Assay, shows that lower Cq values (typically under 29 cycles) correspond to a high quantity of target sequences. With a QCT value of 13.6, we meet industry standards, and delta Cq values consistently remain below 5, confirming the DNA’s high quality for sequencing.

We recognize the critical role of DNA quality from FFPE blocks in NGS workflows. This data, generated using the Infinium HD FFPE QC Assay, shows that lower Cq values (typically under 29 cycles) correspond to a high quantity of target sequences. With a QCT value of 13.6, we meet industry standards, and delta Cq values consistently remain below 5, confirming the DNA’s high quality for sequencing.

We recognize the critical role of DNA quality from FFPE blocks in NGS workflows. This data, generated using the Infinium HD FFPE QC Assay, shows that lower Cq values (typically under 29 cycles) correspond to a high quantity of target sequences. With a QCT value of 13.6, we meet industry standards, and delta Cq values consistently remain below 5, confirming the DNA’s high quality for sequencing.

Sample

A

B

C

D

E

F

Cq

11.9

14.7

13.2

12.8

12.2

11.9

Cq

-1.7

1.1

-0.4

-0.8

-1.4

-1.7

Explore the possibilities

Explore the possibilities

Explore the possibilities

Explore the possibilities

What do you use your extracted DNA for? Access tailored datasets for your workflows:

What do you use your extracted DNA for? Access tailored datasets for your workflows:

What do you use your extracted DNA for? Access tailored datasets for your workflows:

Sequencing

Sequencing

Sequencing

Sequencing

Sequencing

Biobanking

Biobanking

Biobanking

Biobanking

Biobanking

Microarrays

Microarrays

Microarrays

Microarrays

Microarrays

Pharmacogenetics

Pharmacogenetics

Pharmacogenetics

Pharmacogenetics

Pharmacogenetics

Gut microbiome testing

Gut microbiome testing

Gut microbiome testing

Gut microbiome testing

Gut microbiome testing

HLA typing

HLA typing

HLA typing

HLA typing

HLA typing

BCR-ABL testing

BCR-ABL testing

BCR-ABL testing

BCR-ABL testing

BCR-ABL testing

Liquid biopsy research

Liquid biopsy research

Liquid biopsy research

Liquid biopsy research

Liquid biopsy research

See Manta in action

See Manta in action

See Manta in action

See Manta in action

See Manta in action

Schedule a demo with us and see how Manta can make
your workflows more efficient.

Schedule a demo with us and see how Manta can make
your workflows more efficient.

Schedule a demo with us and see how Manta can make
your workflows more efficient.

Schedule a demo with us and see how Manta can make your workflows more efficient.

Schedule a demo with us and see how Manta can make your workflows more efficient.

Schedule your demo now

Schedule your demo now

Schedule your demo now

Schedule your demo now

Schedule your demo now

© Cambrian Biotech Pvt. Ltd.
Bengaluru, Karnataka

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