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Resources

Contact us

Complex library prep,
fully automated

Complex library prep,
fully automated

Complex library prep,
fully automated

Complex library prep,
fully automated

Run validated workflows from Twist, IDT, Illumina, NEB, and SOPHiA GENETICS (or automate your own with our AI-powered protocol builder). Orca delivers precise, reproducible liquid handling to standardize library preparation across every run.

Run validated workflows from Twist, IDT, Illumina, NEB, and SOPHiA GENETICS (or automate your own with our AI-powered protocol builder). Orca delivers precise, reproducible liquid handling to standardize library preparation across every run.

Inside Orca

Engineered for precision

Orca integrates the essential modules needed for automated library preparation, enabling precise liquid handling, temperature control, magnetic separation, and seamless workflow execution on a single platform.

Elevated pipette
tip racks

On-deck
thermal cycler

Hybrid peltier module for
MCTs and PCR strips

Peltier module
for reaction plate

Reagent
reservoir

Micro-centrifuge
tube module

Deck slots for
96-well plates

Magnetic shaker
module

Trash chute

Elevated pipette
tip racks

On-deck
thermal cycler

Hybrid peltier module for
MCTs and PCR strips

Peltier module
for reaction plate

Reagent
reservoir

Micro-centrifuge
tube module

Deck slots for
96-well plates

Magnetic shaker
module

Trash chute

1

1

2

7

6

3

4

5

8

9

Pre-validated protocols

Ready-to-run, straight out of the box

Orca comes with a growing library of pre-validated workflows for leading NGS library preparation kits from Twist, IDT, Illumina, NEB, SOPHiA GENETICS, and other trusted providers. Pick one, load the deck, and press run - no method development required.

  • DNA & RNA library prep for short- and long-read platforms

  • Hybridization capture & target enrichment

  • Locked parameters and audit trail for reproducible results

Walk-away workflow

Load. Select. Walk away.

Step 1:

Step 1:

Step 1:

Load the deck

Load the deck

Load the deck

Step 2:

Step 2:

Step 2:

Pick a protocol

Pick a protocol

Pick a protocol

Step 3:

Step 3:

Step 3:

Press run

Press run

Press run

Step 4:

Step 4:

Step 4:

Monitor remotely

Monitor remotely

Monitor remotely

Vendor-agnostic

Designed for an open ecosystem

AI Protocol Builder

From kit IFU to automated workflow

Upload a kit's IFU, and Orca's AI Protocol Builder automatically converts them into a deck-aware automation workflow. Review and validate every step before running the protocol on the instrument.

Generate your first protocol

Run management software

Powered by Seahorse

Seahorse is the software platform behind Orca, designed to simplify sequencing operations from sample intake to analysis. It manages run planning, sample tracking, LIMS integration, and downstream analysis through a single, connected workflow.

Explore seahorse

Smart run planning

Automatically schedules runs to maximize instrument utilization, minimize reagent waste, and reduce turnaround time.

Smart run planning

Automatically schedules runs to maximize instrument utilization, minimize reagent waste, and reduce turnaround time.

Cross-panel batching

Process multiple assay panels in a single Orca run by sharing common library preparation steps and performing target enrichment in parallel.

Cross-panel batching

Process multiple assay panels in a single Orca run by sharing common library preparation steps and performing target enrichment in parallel.

LIMS connectivity

Seamlessly exchanges sample information, manifests, and runs data with your existing LIMS for uninterrupted laboratory workflows.

LIMS connectivity

Seamlessly exchanges sample information, manifests, and runs data with your existing LIMS for uninterrupted laboratory workflows.

Pipeline management

Automatically triggers secondary and tertiary analysis and tracks every sample through to final report generation.

Pipeline management

Automatically triggers secondary and tertiary analysis and tracks every sample through to final report generation.

Run multiple panels in a single workflow

Run multiple panels in a single workflow

All steps run inside one ORca

All steps run inside one ORca

All steps run inside one ORca

One instrument · one thermal cycler · same chemistry

One instrument · one thermal cycler · same chemistry

One instrument · one thermal cycler · same chemistry

Panels queued

Panels queued

Solid tumour

Solid tumour

Hereditary cancer

Hereditary cancer

Myeloid

Myeloid

Panels queued

Solid tumour

Hereditary cancer

Myeloid

Shared steps

Shared steps

Common adapter ligation

Common adapter ligation

Indexing PCR

Indexing PCR

Same chemistry · one thermal cycler

Same chemistry · one thermal cycler

Shared steps

Common adapter ligation

Indexing PCR

Same chemistry · one thermal cycler

Captures · parallel

Captures · parallel

Capture · panel A

Capture · panel A

Capture · panel B

Capture · panel B

Capture · panel C

Capture · panel C

Captures · parallel

Capture · panel A

Capture · panel B

Capture · panel C

3 panels → 1 ORca run

3 panels → 1 ORca run

Indexed libraries · ready to sequence

Indexed libraries · ready to sequence

3 panels → 1 ORca run

Indexed libraries · ready to sequence

Why labs choose Orca

Features

Features

Orca

Orca

Hamilton

Hamilton

Agilent Magnis

Agilent Magnis

Biomek iGenius

Biomek iGenius

Hands-on time per run

Hands-on time per run

< 10 min

< 10 min

30-60 min

30-60 min

~15 min

~15 min

20-40 min

20-40 min

Validated protocols

Validated protocols

50+ ready

50+ ready

Custom scripts

Custom scripts

Fixed menu

Fixed menu

Limited

Limited

AI protocol builder

AI protocol builder

IFU → run

IFU → run

No

No

No

No

No

No

Protocol validation

Protocol validation

< $0.0025/min

< $0.0025/min

$3,000+/protocol

$3,000+/protocol

Closed cartridge

Closed cartridge

Per-protocol

Per-protocol

Walk-away operation

Walk-away operation

Full run

Full run

Partial

Partial

Fixed run

Fixed run

Partial

Partial

On-device run visualization

On-device run visualization

Yes

Yes

Limited

Limited

Limited

Limited

Limited

Limited

Technical specifications

Technical specifications

Technical specifications

Technical specifications

Bring walk-away library prep to your lab

Schedule a demo with us and see how Orca can make NGS library prep workflows more efficient.

Pre-book now