Isolate high-yield RNA from
FFPE blocks consistently
Isolate high-yield RNA from FFPE blocks consistently
Isolate high-yield RNA from
FFPE blocks consistently
Isolate high-yield RNA from FFPE blocks consistently
Isolate high-yield RNA from
FFPE blocks consistently
The Cambrian FFPE RNA Isolation Kit with Manta delivers high-quality RNA with reliable yield and purity, helping labs achieve reproducible results across cohorts, effortlessly and efficiently.
The Cambrian FFPE RNA Isolation Kit with Manta delivers high-quality RNA with reliable yield and purity, helping labs achieve reproducible results across cohorts, effortlessly and efficiently.
The Cambrian FFPE RNA Isolation Kit with Manta delivers high-quality RNA with reliable yield and purity, helping labs achieve reproducible results across cohorts, effortlessly and efficiently.
The Cambrian FFPE RNA Isolation Kit with Manta delivers high-quality RNA with reliable yield and purity, helping labs achieve reproducible results across cohorts, effortlessly and efficiently.
Available pack size:
Available pack size:
Available pack size:
32 reactions
32 reactions
32 reactions
Designed for the realities
of oncology workflows
Designed for the realities of oncology workflows
Designed for the realities
of oncology workflows
Designed for the realities
of oncology workflows
Designed for the realities
of oncology workflows
Consistent RNA quality
Consistent RNA quality
Consistent RNA quality
Consistent RNA quality
Single-cell transcriptomics
Single-cell transcriptomics
Single-cell transcriptomics
Single-cell transcriptomics
Gene expression profiling
Gene expression profiling
Gene expression profiling
Gene expression profiling
Fusion gene detection
Fusion gene detection
Fusion gene detection
Fusion gene detection
Therapeutic development
Therapeutic development
Therapeutic development
Therapeutic development
Liquid biopsy
Liquid biopsy
Liquid biopsy
Liquid biopsy
Molecular diagnostics
Molecular diagnostics
Molecular diagnostics
Molecular diagnostics
lncRNA and miRNA research
lncRNA and miRNA research
lncRNA and miRNA research
lncRNA and miRNA research
Optimized chemistry counteracts crosslinking and fragmentation, reducing assay failures and delivering RNA with the integrity required for sensitive downstream applications.
Optimized chemistry counteracts crosslinking and fragmentation, reducing assay failures and delivering RNA with the integrity required for sensitive downstream applications.
Optimized chemistry counteracts crosslinking and fragmentation, reducing assay failures and delivering RNA with the integrity required for sensitive downstream applications.
Zero DNA contamination
Zero DNA contamination
Zero DNA contamination
Zero DNA contamination
Integrated DNase treatment safeguards downstream accuracy in expression profiling and biomarker studies.
Integrated DNase treatment safeguards downstream accuracy in expression profiling and biomarker studies.
Integrated DNase treatment safeguards downstream accuracy in expression profiling and biomarker studies.
Maximum RNA recovery
Maximum RNA recovery
Maximum RNA recovery
Maximum RNA recovery
The optimised buffers on Manta deliver reproducible yields, even from small or over-fixed tissue sections.
The optimised buffers on Manta deliver reproducible yields, even from small or over-fixed tissue sections.
The optimised buffers on Manta deliver reproducible yields, even from small or over-fixed tissue sections.
Simply your workflow
Simply your workflow
Simply your workflow
Simply your workflow
Automation makes extraction effortless, process 32 FFPE samples on Manta in just 2.5 hours (after lysis).
Automation makes extraction effortless, process 32 FFPE samples on Manta in just 2.5 hours (after lysis).
Consistency despite FFPE variability
Consistency despite FFPE variability
Consistency despite FFPE variability
Consistency despite FFPE variability
Manual handling of FFPE blocks can cause variability in RNA yield and integrity. Automation standardizes extraction steps → ensuring reproducible, high-quality RNA for downstream PCR, NGS, and molecular assays.
Manual handling of FFPE blocks can cause variability in RNA yield and integrity. Automation standardizes extraction steps → ensuring reproducible, high-quality RNA for downstream PCR, NGS, and molecular assays.
Manual handling of FFPE blocks can cause variability in RNA yield and integrity. Automation standardizes extraction steps → ensuring reproducible, high-quality RNA for downstream PCR, NGS, and molecular assays.
DV200 >70%
DV200 >70%
DV200 >70%
DV200 >70%
Get high-integrity RNA for demanding sensitive applications.
Get high-integrity RNA for demanding sensitive applications.
Get high-integrity RNA for demanding sensitive applications.
Performance preview
Performance preview
Performance preview
Performance preview
Performance preview
RNA yield and purity datasets
RNA yield and purity datasets
RNA yield and purity datasets
RNA yield and purity datasets
RNA yield and purity datasets
From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.
From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.
From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.
From just four 10 µm FFPE curls, the kit delivers ~5,00 ng of RNA (Qubit) with excellent purity (A260/280: 1.9–2.1 & A260/230: 1.5–2.0). The high yield and quality make it ideal for demanding applications such as BCR-ABL testing and RNA-seq, ensuring reliable results and seamless downstream compatibility.
Yield (ng)
Yield (ng)
Yield (ng)
A260/A280
A260/A280
A260/A280
A260/A230
A260/A230
A260/A230
Sample number
Qubit yield (ng)
500
1000
5000
10000
8
7
6
5
4
3
2
1
0.0
0.5
1.0
1.5
2.0
2.5
Purity ratio
Sample number
Qubit yield (ng)
500
1000
5000
10000
8
7
6
5
4
3
2
1
0.0
0.5
1.0
1.5
2.0
2.5
Purity ratio
Sample number
Qubit yield (ng)
500
1000
5000
10000
8
7
6
5
4
3
2
1
0.0
0.5
1.0
1.5
2.0
2.5
Purity ratio
Sample number
Qubit yield (ng)
500
1000
5000
10000
8
7
6
5
4
3
2
1
0.0
0.5
1.0
1.5
2.0
2.5
Purity ratio
Sample number
Qubit yield (ng)
500
1000
5000
10000
8
7
6
5
4
3
2
1
0.0
0.5
1.0
1.5
2.0
2.5
Purity ratio
RIN & DV200 values
RIN & DV200 values
RIN & DV200 values
RIN & DV200 values
RIN & DV200 values
DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.
DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.
DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.
DV200, the percentage of RNA fragments longer than 200 nucleotides, is a key metric for RNA-seq suitability (Illumina). Even with low-quality FFPE blocks, our kit consistently delivers high RNA yields that meet sequencing input requirements. While both DV200 and RIN values depend on the intrinsic quality of FFPE samples, our kit ensures reliable performance, with RIN values typically ranging from 1.9 to 3.8.
Sample number
Sample number
Sample number
1
1
1
2
2
2
3
3
3
4
4
4
5
5
5
6
6
6
7
7
7
8
8
8
RIN
RIN
RIN
3.8
3.8
3.8
3.1
3.1
3.1
3.2
3.2
3.2
2.1
2.1
2.1
1.7
1.7
1.7
2.1
2.1
2.1
1.8
1.8
1.8
2.6
2.6
2.6
DV200 (%)
DV200 (%)
DV200 (%)
85.47
85.47
85.47
73.09
73.09
73.09
83.59
83.59
83.59
60.23
60.23
60.23
40.7
40.7
40.7
32.1
32.1
32.1
34.58
34.58
34.58
58.91
58.91
58.91
Optimized for
critical downstream assays
Gene expression profiling
Tumor subtype classification
Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)
Biomarker discovery & validation
Transcriptome studies
RNA fusions & splice variants
Retrospective clinical research
Optimized for critical downstream assays
Gene expression profiling
Tumor subtype classification
Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)
Biomarker discovery & validation
Linking RNA signatures to prognosis
Therapy response
Disease progression
Transcriptome studies
Global expression profiling
Whole-transcriptome RNA-seq for personalized oncology
RNA fusions & splice variants
Detect clinically relevant gene fusions
Characterize splice isoforms linked to cancer biology
Retrospective clinical research
Mining archived FFPE archives for relapse, survival, and long-term outcome correlations
Optimized for critical downstream assays
Gene expression profiling
Tumor subtype classification
Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)
Biomarker discovery & validation
Linking RNA signatures to prognosis
Therapy response
Disease progression
Transcriptome studies
Global expression profiling
Whole-transcriptome RNA-seq for personalized oncology
RNA fusions & splice variants
Detect clinically relevant gene fusions
Characterize splice isoforms linked to cancer biology
Retrospective clinical research
Mining archived FFPE archives for relapse, survival, and long-term outcome correlations
Optimized for
critical downstream assays
Gene expression profiling
Tumor subtype classification
Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)
Biomarker discovery & validation
Transcriptome studies
RNA fusions & splice variants
Retrospective clinical research
Optimized for
critical downstream assays
Gene expression profiling
Tumor subtype classification
Immune profiling (e.g., HER2+ vs. triple-negative breast cancer)
Biomarker discovery & validation
Transcriptome studies
RNA fusions & splice variants
Retrospective clinical research
Seamlessly integrates
with your lab needs
Seamlessly integrates
with your lab needs
Seamlessly integrates
with your lab needs
Seamlessly integrates
with your lab needs
Seamlessly integrates
with your lab needs
Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.
Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.
Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.
Effortlessly adapts to any lab workflow, from low-throughput manual research to high-throughput automated processing, without the need to redesign protocols.
Technical specifications
Technical specifications
Technical specifications
Technical specifications
FAQs
How does your kit perform on older or over-fixed FFPE blocks?
How many FFPE samples can Manta process in a single run?
What is the hands-on time vs. total run time?
How much RNA can I expect from a sample?
Is the kit RUO or IVD?
What customizations are available?
FAQs
FAQs
FAQs
How does your kit perform on older or over-fixed FFPE blocks?
How many FFPE samples can Manta process in a single run?
What is the hands-on time vs. total run time?
How much RNA can I expect from a sample?
Is the kit RUO or IVD?
What customizations are available?
Simplify your workflows
Simplify your workflows
Simplify your workflows
Simplify your workflows
Recover high-integrity RNA for sensitive assays.
Recover high-integrity RNA for sensitive assays.
Recover high-integrity RNA for sensitive assays.
Recover high-integrity RNA for sensitive assays.
Recover high-integrity RNA for sensitive assays.