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CamSelect Long

CamSelect Long

CamSelect Long

CamSelect Long

CamSelect Long

Increase usable Gb per long-read sequencing flow cell by up to 3x

Increase usable Gb per long-read sequencing flow cell by up to 3x

Increase usable Gb per long-read sequencing flow cell by up to 3x

Increase usable Gb per long-read sequencing flow cell by up to 3x

SKU:

SKU:

SKU:

CBWD018

Pack size:

Pack size:

Pack size:

50 preps

50 preps

50 preps

CamSelect magnetic beads for DNA size selection and PCR clean-up in library preparation for next-generation sequencing workflows
CamSelect magnetic beads for DNA size selection and PCR clean-up in library preparation for next-generation sequencing workflows

A new standard for
long-read preparation

Long-read sequencing platforms have finite capacity per run, constrained by pore availability and functional lifetime. In heterogeneous samples, short DNA fragments can generate large volumes of low-information reads while consuming valuable sequencing bandwidth.

CamSelect Long addresses this challenge through tunable cutoff (under 2kb, 5kb, 7kb and 10kb), enriching libraries for longer fragments. This improves the proportion of informative long reads, increases read N50 and pass yield, stabilizes run performance, and enables greater usable data output per flow cell.

Improves read N50 and long-read fraction

Increased usable Gb per flowcell for long read sequencing

Increases pass yield (Q ≥ threshold)

Enhances pore retention and flow-cell efficiency

Low input requirement (≈1 µg DNA)

Automation-ready magnetic bead chemistry

Maximize data yield per read

Maximize data yield per read

Maximize data yield per read

Maximize data yield per read

CamSelect Long improves data yield and N50 while reducing pore consumption, delivering more contiguous assemblies. Libraries were prepared using the Oxford Nanopore technologies (ONT) Native Barcoding Ligation kit (EXP-NBD114) according to manufacturer’s protocol, and sequenced on a PromethION 2 Solo platform with FLO-PRO114M flowcell to a target depth of 5 Gb per sample.

CamSelect Long improves data yield and N50 while reducing pore consumption, delivering more contiguous assemblies. Libraries were prepared using the Oxford Nanopore technologies (ONT) Native Barcoding Ligation kit (EXP-NBD114) according to manufacturer’s protocol, and sequenced on a PromethION 2 Solo platform with FLO-PRO114M flowcell to a target depth of 5 Gb per sample.

Metric

Metric

No cleanup
(control)

No cleanup
(control)

CamSelect
Long™

CamSelect
Long™

Improvement
(%)

Improvement
(%)

Metric

No cleanup
(control)

CamSelect
Long™

Improvement
(%)

Metric

No cleanup
(control)

CamSelect
Long™

Improvement
(%)

Total yield

1.7 Gb

5.5 Gb

223.50%

Total yield

1.7 Gb

5.5 Gb

223.50%

Read length N50

4,745 bp

7419 bp

56.40%

Read length N50

4,745 bp

7419 bp

56.40%

Mean read length

3416 bp

5152 bp

50.80%

Mean read length

3416 bp

5152 bp

50.80%

Long read fraction>10kb

4.70%

11.90%

153.20%

Long read fraction>10kb

4.70%

11.90%

153.20%

Stool-derived and saliva-derived DNA was analyzed on the Agilent TapeStation System before and after treatment with CamSelect LongTM. The results are depicted below.

Stool-derived and saliva-derived DNA was analyzed on the Agilent TapeStation System before and after treatment with CamSelect LongTM. The results are depicted below.

Post analysis

Post analysis

Untreated
sample

Untreated
sample

Sample treated with
Camselect Long™

Sample treated with
Camselect Long™

Post analysis

Untreated
sample

Sample treated with
Camselect Long™

Post analysis

Untreated
sample

Sample treated with
Camselect Long™

% reads mapping to human host

1.17

0.278

% reads mapping to human host

1.17

0.278

Assembled data

79 mb

192 mb

Assembled data

79 mb

192 mb

MAGS

43

116

MAGS

43

116

In stool samples, cleanup and size-selection prior to library preparation reduced host-mapped reads, increased total assembled sequence length, and substantially improved recovery of metagenome-assembled genomes (MAGs).

In stool samples, cleanup and size-selection prior to library preparation reduced host-mapped reads, increased total assembled sequence length, and substantially improved recovery of metagenome-assembled genomes (MAGs).

Purpose-built for long-read sequencing economics

Long-read whole-genome sequencing (WGS)

Metagenomics and microbiome sequencing

Structural variant detection

De novo genome assembly

MAG recovery and assembly

Manta empowers diverse molecular diagnostic applications including genetics lab, gut microbiome testing, germline mutation detection, microarray testing

Purpose-built for long-read sequencing economics

Long-read whole-genome sequencing (WGS)

Metagenomics and microbiome sequencing

Structural variant detection

De novo genome assembly

MAG recovery and assembly

Manta empowers diverse molecular diagnostic applications including genetics lab, gut microbiome testing, germline mutation detection, microarray testing

Purpose-built for long-read sequencing economics

Long-read whole-genome sequencing (WGS)

Metagenomics and microbiome sequencing

Structural variant detection

De novo genome assembly

MAG recovery and assembly

Purpose-built for long-read sequencing economics

Long-read whole-genome sequencing (WGS)

Metagenomics and microbiome sequencing

Structural variant detection

De novo genome assembly

MAG recovery and assembly

Workflow overview

Workflow overview

Workflow overview

Workflow overview

Workflow overview

Illumina NGS Library Prep

Illumina NGS Library Prep

Illumina NGS Library Prep

Illumina NGS Library Prep

NovaSeq

NovaSeq

NovaSeq

NovaSeq

NovaSeq

NextSeq

NextSeq

NextSeq

NextSeq

NextSeq

MiSeq

MiSeq

MiSeq

MiSeq

MiSeq

CamSelect NGS removes excess primers and unwanted fragments after PCR, ensuring cleaner libraries. In dual-index workflows, it’s also used post-indexing PCR to improve purity before sequencing.

Streamline your nucleic acid extraction with a magnetic stand that’s designed for consistency, speed, and ease of use.

Streamline your nucleic acid extraction with a magnetic stand that’s designed for consistency, speed, and ease of use.

CamSelect NGS removes excess primers and unwanted fragments after PCR, ensuring cleaner libraries. In dual-index workflows, it’s also used post-indexing PCR to improve purity before sequencing.

DNA extraction

DNA extraction

DNA extraction

DNA extraction

DNA extraction

PCR Amplification

PCR amplification

PCR amplification

Clean-up

Clean-up

Clean-up

PCR amplification

Clean-up

PCR amplification

Clean-up

Library QC

Library QC

Library QC

Library QC

Library QC

Normalization & pooling

Normalization & pooling

Normalization & pooling

Normalization & pooling

Normalization & pooling

Sequencing

Sequencing

Sequencing

Sequencing

Sequencing

Target Enrichment

Target Enrichment

Target Enrichment

Target Enrichment

Agilent SureSelect

Agilent SureSelect

Agilent SureSelect

Agilent SureSelect

Agilent SureSelect

IDT xGen

IDT xGen

IDT xGen

IDT xGen

IDT xGen

Twist

Twist

Twist

Twist

Twist

CamSelect NGS clean-up removes oligo contamination, excess primers, and short artifacts, delivering higher yield, greater purity, and more reliable sequencing in target enrichment workflows.

Streamline your nucleic acid extraction with a magnetic stand that’s designed for consistency, speed, and ease of use.

Streamline your nucleic acid extraction with a magnetic stand that’s designed for consistency, speed, and ease of use.

CamSelect NGS clean-up removes oligo contamination, excess primers, and short artifacts, delivering higher yield, greater purity, and more reliable sequencing in target enrichment workflows.

DNA extraction

DNA extraction

DNA extraction

DNA extraction

DNA extraction

Library preparation

Library preparation

Library preparation

Library preparation

Library preparation

Hybrid capture

Hybrid capture

Hybrid capture

Hybrid capture

Hybrid capture

NGS clean-up

NGS clean-up

NGS clean-up

NGS clean-up

NGS clean-up

QC and sequencing

QC and sequencing

QC and sequencing

QC and sequencing

QC and sequencing

Improve pore utilization

Elevate your sequencing workflows

Elevate your
sequencing workflows

Get more usable genomic data from every sequencing run.

Contact us now to learn how CamSelect NGS can improve your sequencing workflows.

Get more usable genomic data from every sequencing run.